Interpretation of Electrospray Mass Specta of Small Molecules
Presented by Earl Michael Thurman, University of Colorado
Tuesday, May 3, 2022 ◉ 1:00 pm to 3:00 pm EST
COURSE DESCRIPTION: There is a need for a course that looks directly at the spectra coming from the LC/MS instruments and how to interpret the spectra and their various fragment ions. This course will address the important topics of how ionization and fragmentation occurs, what compounds are readily analyzed, and how to interpret the spectra for absolute identity of unknowns from all types of mass spectrometers, including single quadrupole (MS), triple quadrupole (MS/MS), ion trap (MS/MS), Q-TOF (MS/MS with accurate mass), LC/TOF-MS (accurate mass fragmentations), Orbitrap MS and the new technology Ion Mobility Mass Spectrometry. The course should appeal to a broad audience including all professionals in analytical chemistry.
TARGET AUDIENCE: A Target audience includes all Chemistry, Pharmaceutical, and Environmental professionals that work on organic analytical methods, interpretation of spectra, and unknown analysis.
LEARNING OBJECTIVES: There are five learning objectives: 1. Explain how ions form in the source of the mass spectrometer. 2. How ions fragment into stable product ions following 5 pathways of fragmentation. 3. How to interpret the fragment ions and do unknown analysis. 4. Introduction into the various software programs available to interpret LC mass spectra. 5. Enable the student to pull all of the knowledge together to solve problems in pharmaceutical, environmental, and other applied areas of mass spectrometry.
CATEGORIES: Atmospheric Pressure Ionization, Environmental Analysis, Ion-Mobility Spectrometry, Liquid Chromatography-Mass Spectrometry, Pharmaceutical Sciences
About the Instructor