Award Sessions: Monday, April 11
Monday, April 11 ◉ 1:00 pm EST
ACS Analytical Division Satinder Ahuja Award for Young Investigators in Separation Science
Awardee: James P. Grinias, Rowan University
Introduction: Amber Hupp
Chromatographic Approaches to Measuring Pharmaceutical and Biological Compounds
Over the past decade, a variety of advances in liquid chromatography columns and instrumentation have enabled improved capabilities for measuring pharmaceutical and biological analytes in a broad array of sample types. Initial studies on the impact of viscous friction in columns packed with superficially porous particles have guided the development of high-throughput LC methods for isocratic analysis of pharmaceutical compounds and gradient analysis of neurotransmitters. Strategies for packing capillary LC columns have been applied in microfluidic SPE-MS platforms for monitoring cellular lipid secretion and in integrated column cartridges for portable LC analysis. Data acquisition devices based on microcontrollers and single-board computers have been expanded to control capillary-scale pumping devices and regulate voltage for electrospray ionization in LC-MS applications. This broad array of strategies is now being expanded to improve the characterization of biopharmaceutical compounds.
Talanta Medal Award
Awardee: Joseph Wang, University California San Diego, La Jolla
Introduction: Gary Christian
Electrochemical Sensors: From Beakers to the Skin
Electrochemical systems and sensors have experienced remarkable changes in recent years. The rising demands for wearable and point-of-care electrochemical sensors have led to growing needs to move from benchtop instruments to truly portable miniaturized electrochemical analyzers and epidermal platforms capable of decentralized and on-body electrochemical measurements. The new generation of wearable electrochemical sensors offers continuous molecular information on dynamically changing chemical constituents of different biofluids in a non-invasive manner toward diverse biomedical, wellness, or security applications. This presentation will discuss recent developments in the field of wearable electrochemical sensors integrated directly on the epidermis, on textiles or within the mouth for various non-invasive biomedical monitoring applications. Particular attention will be given to non-invasive monitoring of metabolites and electrolytes using flexible amperometric and potentiometric sensors, respectively, along with related materials and integration considerations. These include advanced materials for imparting remarkable stretchability and self-healing abilities to enable epidermal biosensors to endure extreme deformations experienced by the human skin. We will also discuss the creation of labs under the skin based on arrays of microneedle sensors. The preparation and characterization of such wearable electrochemical sensors will be described, along with their current status and future prospects and challenges.